Imaging and COVID-19
Research type
Research Study
Full title
Radiological imaging in patients tested for COVID-19
IRAS ID
286116
Contact name
Michelle Claire Williams
Contact email
Sponsor organisation
University of Edinburgh
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
It has become apparent that patients with co-morbidities have an increased risk of mortality from coronarvirus disease 2019 (COVID-19). However, the impact of subclinical respiratory and cardiovascular disease on the outcome of patients with COVID-19 is currently unknown.
Subclinical respiratory and cardiovascular disease can be identified on radiological imaging. For example, calcification in blood vessels can identify cardiovascular disease, intra-thoracic and intra-abdominal fat is associated with coronary artery disease, and lung diseases can be identified on CT and x-ray. The impact these radiological features on the outcomes of patients with COVID-19 is currently unknown.
This study aims to assess the radiological imaging of patients tested for COVID-19 in order to identify the presence of co-existing respiratory and cardiovascular disease and assess their impact on clinical outcomes.
All patients tested for COVID-19 with current or previous (last 3 years) radiological imaging will be included in this study. Information on COVID-19 tests and clinical factors will be obtained from the DataLoch team who are already collecting and processing this data. Additional clinical information will be obtained from electronic health records as required. Radiological images will be identified and review on the PACS (picture archiving and communication system) and will be de-identified at Edinburgh Imaging for subsequent image analysis.
REC name
Wales REC 7
REC reference
20/WA/0184
Date of REC Opinion
26 Jun 2020
REC opinion
Favourable Opinion