iDiabetes
Research type
Research Study
Full title
The iDiabetes Platform: Enhanced Phenotyping of patients with diabetes for Precision Diagnosis, Prognosis and Treatment
IRAS ID
318454
Contact name
Ewan Pearson
Contact email
Sponsor organisation
University of Dundee
Duration of Study in the UK
15 years, 0 months, 1 days
Research summary
The intelligent Diabetes platform will add precision approaches using computer algorithms and biomarkers to improve outcomes for patients with diabetes. We will compare 3 groups in a cluster randomised study across GP practices in NHS Tayside:
1. Usual care - no input from iDiabetes
2. iDiabetes - promoting current guideline care
3. iDiabetesPlus -‘Enhanced phenotyping’ of patients using additional clinical tests undertaken on routine blood samples – including tests of heart function (BNP and hsTroponin) and for liver fat & fibrosis (scarring), as well as tests for insulin production and resistance. We will also include DNA tests to allow the use of ‘genetic risk scores’ to flag people at increased risk of heart disease.
Over 15 months patients will take part in iDiabetes at their annual diabetes reviews. We will use the clinical data routinely collected at this review, along with test results for the iDiabetesPlus group, to make personalised recommendations for treatment and further investigations such as ECHO and Fibroscan. Clinical staff will access this information via the iDiabetes platform and will discuss all recommendations with the patient. iDiabetes only recommends; patients and their health care team will decide together what is best for them.
The platform will monitor patients and continue to make recommendations for 3 years with long terms outcomes being assessed through linked data over 15 years.
By comparing the groups over time we will assess if the iDiabetes platform is effective and cost-efficient, enabling the roll out of precision diabetes care beyond Tayside. This will be a collaborative approach between researchers, clinical staff, NHS, SCI-Diabetes and MyWayDigitalHealth.
REC name
East of Scotland Research Ethics Service REC 2
REC reference
23/ES/0008
Date of REC Opinion
6 Apr 2023
REC opinion
Further Information Favourable Opinion