ICONIC-M

  • Research type

    Research Study

  • Full title

    ICONIC-M: IMPROVING CRT OUTCOME WITH NON-INVASIVE CARDIAC MAPPING A multicentre randomised controlled study to assess patient response to CRT comparing ECGI map-guided left ventricular lead placement with empirical lead placement.

  • IRAS ID

    319015

  • Contact name

    Tim Betts

  • Contact email

    tim.betts@ouh.nhs.uk

  • Sponsor organisation

    EP Solutions SA

  • Clinicaltrials.gov Identifier

    NCT05564793

  • Duration of Study in the UK

    2 years, 10 months, 31 days

  • Research summary

    The purpose of this clinical investigation it to collect data with a non-invasive medical system, named ‘Amycard 01C’. The device will only contact the outside of the body.

    The Amycard 01C-system is a CE-marked device approved and sold on the European and British markets. With the device, it is possible to see and map the function of the heart.

    In this study, we look at how the Amycard 01C-system may help to further improve and optimise Cardiac Resynchronisation Therapy (CRT), compared to regular CRT.

    As the data from the Amycard 01C-system can map the heart and better understand how it beats, it is hoped be able to place the pacemaker wires, which are part of a CRT device, more accurately.

    If the pacemaker wires are placed more accurately, the CRT-therapy may be more effective.

    In this study, it is hoped to demonstrate this effect.

  • REC name

    West Midlands - Edgbaston Research Ethics Committee

  • REC reference

    24/WM/0033

  • Date of REC Opinion

    24 Apr 2024

  • REC opinion

    Further Information Favourable Opinion