Hypohydration and cardiorespiratory function

• Research type

  Research Study

• Full title

  Clinical observational study of the effect of hypohydration upon cardiorespiratory function

• IRAS ID

  94547

• Contact name

  James Prentis

• Contact email

  james.prentis@nuth.nhs.uk

• Sponsor organisation

  Newcastle Upon Tyne Hospitals NHS Foundation Trust

• Clinicaltrials.gov Identifier

  NCT01949350

• Research summary

  All patients are starved for a minimum of 6 hours before major surgery. There is evidence in athletes that this can adversely affect cardiorespiratory function which has been shown to be an important determinant of outcome after major surgery. This study aims to assess whether cardiorespiratory function is affected by the routine preoperative starvation policy.
  We plan to undertake a cardiopulmonary exercise test under similar conditions as the starvation policy states from the Royal College of anaesthetists and repeat the test on another day after the patient has taken carbohydrate drinks the day before and on the day of the test.

• REC name

  North East - Newcastle & North Tyneside 1 Research Ethics Committee

• REC reference

  13/NE/0321

• Date of REC Opinion

  23 Dec 2013

• REC opinion

  Further Information Favourable Opinion