How stress effects descision making in borderline personality disorder

  • Research type

    Research Study

  • Full title

    A study to investigate the effect of stress on decision making in borderline personality disorder.

  • IRAS ID

    153767

  • Contact name

    Alice Oates

  • Contact email

    alice.oates@slam.nhs.uk

  • Sponsor organisation

    King's College London

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    The study aims to characterise how induced stress alters the neuropsychological and physiological response differently in patients with borderline personality disorder (BPD) compared to controls.

    In this study, up to 40 patients with borderline personality disorder and 40 healthy controls aged between 18-65 years will be recruited. They will each attend one study session. In this session they will repeat a decision making task on three occasions, once after a brief period of stress induction by way of the Trier Social Stress Test (a frequently used and well validated method of replicating psychosocial stress).

    We will check the effect of stress on decision making using:
    -the results and data collected by the decision-making task
    -salivary cortisol levels and measures of heart rate during the tasks
    -questionnaires

    Participants will only be involved in the study on the day of assessment.

    The study is being departmentally funded.

    The study will take place at a location convenient for participants- either the Centre from Neuroimaging Sciences, or another suitable SLaM site. It is thought that participants will spend less than 4 hours in the department on the test day itself. They will be modest remuneration for participants - twenty pounds per person.

  • REC name

    London - Chelsea Research Ethics Committee

  • REC reference

    15/LO/1528

  • Date of REC Opinion

    13 Oct 2015

  • REC opinion

    Further Information Favourable Opinion