holistic management of diabetes secondary to chronic pancreatitis
Research type
Research Study
Full title
Improving diagnosis and holistic management of diabetes secondary to chronic pancreatitis: A mixed methods study
IRAS ID
332753
Contact name
James Shaw
Contact email
Sponsor organisation
Newcastle upon Tyne Hospitals Foundation Trust
Duration of Study in the UK
2 years, 1 months, 31 days
Research summary
Background:
Chronic pancreatitis (CP) is a long-term condition. It develops when the pancreas, an organ in the abdomen, becomes inflamed. The pancreas makes digestive juices and hormones such as insulin (which is responsible for helping the body use sugar for energy). CP causes pain and problems with digestion and production of insulin. Reduced insulin, due to pancreas damage, results in sugar levels becoming too high, leading to diabetes (known as Type 3c diabetes). This type of diabetes is poorly researched so we know little about the experiences of people living with CP related diabetes or the best treatment options for them.
Aims
The aim of this project is to improve the diagnosis and management of diabetes in people living with CP, reducing complications from diabetes and improve quality of life (QoL).
Project design:
This project will comprise of two studies:
Study A: Understanding how/why blood sugar control changes over time in people with CP. 140 participants (including 20 healthy volunteers) will be recruited to have blood tests taken to show how the pancreas controls blood sugar levels. Repeat tests, after 12 months, will be conducted to note any changes and what factors may have contributed to them.
Study B (Sub-study): Explore the experiences of people living with diabetes and CP. 20 participants will be selected from study A who have confirmed diabetes due to CP. One-to-one interviews will be conducted to identify experiences and support that people with CP and diabetes may need.
Impact on patient care:
The results of Study A and Study B will help in the design of a trial to test treatments specific to the management of type 3c diabetes. They will support the development of larger studies and guidelines specifically for this form of diabetes to improve QoL of people living with CP.REC name
Wales REC 3
REC reference
24/WA/0165
Date of REC Opinion
27 Jun 2024
REC opinion
Further Information Favourable Opinion