HIIT in progressive MS
Research type
Research Study
Full title
The effect of High Intensity Interval Training on cardiovascular fitness in people with progressive Multiple Sclerosis.
IRAS ID
214650
Contact name
Evan Campbell
Contact email
Sponsor organisation
NHS Ayrshire & Arran
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 7 months, 1 days
Research summary
The aim of this study is to assess the feasibility of a randomised controlled trial comparing the effectiveness of a high intensity interval training exercise program to a continuous moderate exercise program in increasing cardiovascular fitness in people with progressive multiple sclerosis.
The study will recruit 20 people with progressive multiple sclerosis from NHS Ayrshire and Arran. Potential participants will be informed of the study and provided with a participant information sheet. Potential participants who are interested in taking part will be screened for the inclusion/exclusion criteria. If a potential participant meets the inclusion/exclusion criteria written informed consent will be obtained from them and from their GP after which baseline assessments will be completed.
Participants will be randomised to receive either 8 weeks of high intensity interval training or 8 weeks of continuous moderate training. Both training programs will be on an exercise bike and will be carried out twice weekly in the Douglas Grant Rehabilitation Centre in Ayrshire Central Hospital
The interval training group will perform 6x 90 second exercise bouts at 80-95% of their maximal heart rate interspersed with 90 second intervals of working rest to bring their heart rate down to 60-70% of their maximal heart rate. After the last working rest there will be a 3 minute cool down and an opportunity for the participant to rest for up to one hour. The continuous training group will cycle for 30 minutes at 60-70% of their maximal heart rate and then have a 3 minute cool down and the opportunity to rest.
Study assessments will be at baseline, and one week post intervention (9 weeks after start of trial).
REC name
West of Scotland REC 4
REC reference
17/WS/0005
Date of REC Opinion
18 Jan 2017
REC opinion
Favourable Opinion