High volume injections for achilles tendinopathy version 01

  • Research type

    Research Study

  • Full title

    Treating Achilles tendon pain- A feasibility study of saline injection verses exercise

  • IRAS ID

    206837

  • Contact name

    John A Veto

  • Contact email

    jveto@qmu.ac.uk

  • Sponsor organisation

    Research and Enterprise Dept, University of Stirling

  • Duration of Study in the UK

    1 years, 2 months, 2 days

  • Research summary

    A study to assess the feasibility of carrying out a Randomised Control Trial (RCT) to evaluate the effectiveness of injecting a high volume mix of saline and local anaesthetic under ultrasound guidance(trial group)around a thickened painful achilles tendon verses the current conservative approach of an eccentric loading exercise programme(control). Participants will be randomised into 2 groups with the trial group receiving the high volume ultrasound guided injection whilst the control group will carry out an eccentric loading exercise programme. The primary aim of the study will be to evaluate three key areas, of recruitment, follow up and safety. Secondary aims will evaluate the effectiveness of the intervention on pain and function, tendon thickness and neovascularity (formation of new blood vessels in damaged tissue). The VISA-A questionnaire (a validated questionnaire used to evaluate pain and function associated specifically with Achilles tendons) will be administered prior to the commencement of the study and again at 3 months to evaluate pain and function. Neovascularity and tendon thickness will be measured using ultrasound again prior to commencement of the study and at 3 months. Although hypothesis testing is not being carried out, some indication of trends in outcome will be useful regarding feasibility and establishing sample size for a suitable powered future RCT.

  • REC name

    South East Scotland REC 02

  • REC reference

    17/SS/0107

  • Date of REC Opinion

    12 Dec 2017

  • REC opinion

    Further Information Favourable Opinion