High flow nasal oxygen after lung resection surgery
Research type
Research Study
Full title
The efficacy of prophylactic nasal high flow oxygen compared with standard oxygen therapy in improving early postoperative recovery after lung resection surgery.
IRAS ID
148374
Contact name
Andrew A Klein
Contact email
Sponsor organisation
Papworth Hospital NHS Trust
Research summary
Patients post lung resection surgery are at risk of respiratory complications, and consequently delayed recovery and poorer outcomes. Non invasive positive pressure ventilation is one therapy which when administered prohylactically can improve functional performance and decrease respiratory complications. Use of prophylactic NIV therapy is however often limited by increased staffing and monitoring requirements, and in many centres cannot be administered outside of an intensive care or high dependency unit. Nasal high flow oxygen is capable of providing a low level of continuous pressure which helps patients to breathe more efficiently, and may provide the benefits of NIV to post lung resection patients, in a manner simple and convenient enough to use on a standard postoperative ward.
Our hypothesis is that prophylactic use of nasal high flow oxygen for 24 hours post lung resection will improve patients functional recovery, as measured using a 6 minute walking test. Improved functional recovery may be associated with fewer respiratory complications and may subsequently lead to earlier discharge from hospital. We will also measure patients lung function tests before and after their surgery, and evaluate their recovery using an established peri-operative questionnaire.REC name
East Midlands - Derby Research Ethics Committee
REC reference
14/EM/0105
Date of REC Opinion
19 Mar 2014
REC opinion
Further Information Favourable Opinion