Hepatitis B childhood booster study

• Research type

  Research Study

• Full title

  An observational study of children immunised in infancy against hepatitis B virus, evaluating the persistence of immunity and the immune response to a scheduled booster dose of hepatitis B vaccine

• Eudract number

  2008-004785-98

• ISRCTN Number

  N/A

• Clinicaltrials.gov Identifier

  N/A

• Research summary

  The UK immunisation guidelines recommend that children immunised with an accelerated course of hepatitis B vaccine (i.e. vaccination at 0, 1, 2 and 12 months) receive an additional booster dose of vaccine in later childhood (usually at 3 1/2 years of age). The primary objective of this study is to assess what proportion of these children have 'protective' concentrations (> 10mIU/ml) of hepatitis B specific antibodies before and after the booster dose of hepatitis B vaccine.

• REC name

  South Central - Oxford C Research Ethics Committee

• REC reference

  08/H0606/136

• Date of REC Opinion

  9 Dec 2008

• REC opinion

  Favourable Opinion