Haemostatic abnormalities and VITT
Research type
Research Study
Full title
Defining the haemostatic abnormalities associated with Vaccine induced thrombosis and thrombocytopenia (VITT)
IRAS ID
300610
Contact name
Nicola Mutch
Contact email
Sponsor organisation
University of Aberdeen & NHS Grampian
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Patients with VITT usually die of blood clots. We will investigate aspects of blood clot formation and clot resolution/lysis in patients with suspected VITT, comparing the findings in patients with established VITT with those in suspected but non-confirmed cases. This restrospective study will be performed on surplus material from samples sent to NHS Grampian for anti-PF4 testing from around Scotland to conclude a diagnosis of VITT based on current criteria. We have a total of 127 samples available to us of which 55 are anti-PF4 positive and 72 are negative for the anti-PF4 test.
REC name
London - Stanmore Research Ethics Committee
REC reference
21/FT/0087
Date of REC Opinion
13 Jul 2021
REC opinion
Favourable Opinion