Haemodynamics in obese & nonobese pregnants after anaesthesia(V1.0
Research type
Research Study
Full title
Comparative study of haemodynamic changes after spinal anaesthesia in non-obese and obese pregnant women
IRAS ID
149258
Contact name
Naveen Ullal Kirodian
Contact email
Research summary
Obesity has become one of the most common risk factors in obstetric practice. These patients have limited physiological reserves and cardiovascular co morbidities when compared to non-obese pregnant women. The haemodynamic changes associated with spinal anaesthesia pose the greatest hazard to the mother and the foetus and should be avoided. The difference between the changes in haemodynamic variables like cardiac output (CO), stroke volume (SV) and systemic vascular resistance (SVR) between obese and non-obese pregnant women having caesarean section (CS) with spinal anaesthesia has not been studied before.
This study compares the haemodynamic changes after spinal anaesthesia for CS in non-obese and obese parturients, using LIDCORapidv2, which is a noninvasive method of measuring haemodynamic variables. It is a single centre, prospective, case control study. The primary outcome compares the differences in CO, SV and SVR in the two groups. The secondary outcomes include comparison of the correlation between changes in blood pressure (BP) and CO in each patient and the difference in BP between conventional intermittent oscillometric device and continuous LIDCORapidv2 in each patient with a view to assess the need for measurement of cardiac output in obstetric anaesthesia. Foetal outcomes (foetal blood gas and APGAR scoring) as well as the use of vasopressors will be recorded.
REC name
North of Scotland Research Ethics Committee 1
REC reference
14/NS/1025
Date of REC Opinion
29 Aug 2014
REC opinion
Further Information Favourable Opinion