Genetic Analysis of the FAST study
Research type
Research Study
Full title
Genetic Analysis of the FAST study
IRAS ID
335110
Contact name
Stuart Ralston
Contact email
Sponsor organisation
University of Edinburgh
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
3 years, 0 months, 7 days
Research summary
The research study will involved conduction a genome wide association study in participants of FAST who gave consent for a blood samples to be collected for genetic analysis. The proposed analysis will look at the genetic profile of FAST participants and slso seek to identify genetic markers which are associated with urate lowering properties of alluporinol and febuxostat (the drugs used in the study) as well as adverse effects and gout flares. The research will also seek to determine if genetic variables area associated with baseline characteristics of participants and if these differ with population based controls.
REC name
South West - Central Bristol Research Ethics Committee
REC reference
24/SW/0035
Date of REC Opinion
3 Apr 2024
REC opinion
Favourable Opinion