Genes for CMV; v1.0

• Research type

  Research Study

• Full title

  A blinded, case control study to identify genetic determinants of cytomegalovirus infection using exome mapping in solid organ transplant recipients at the Royal Free Hospital.

• IRAS ID

  133965

• Contact name

  Paul Griffiths

• Contact email

  p.griffiths@ucl.ac.uk

• Sponsor organisation

  Royal Free Hospital R&D department

• Research summary

  Cytomegalovirus infection continues to be one of the most common infections after solid organ transplantation despite recent advances in clinical management, it affects between 8.1-20.5% of transplant recipients. It is not known if the transplant recipient’s genes predispose or protect against infection. Discovery of genes that influence the risk of CMV infection could help identify mechanisms for increased susceptibility to virus infection and define groups of patients for early antiviral therapy.

• REC name

  London - Queen Square Research Ethics Committee

• REC reference

  13/LO/1131

• Date of REC Opinion

  29 Aug 2013

• REC opinion

  Favourable Opinion