GCSPD-Pilot Study

• Research type

  Research Study

• Full title

  Gluco Corticosteroid Therapy For Symphysis Pubis Dysfunction-Pilot Study (GCSPD-Pilot Study)

• IRAS ID

  27690

• Contact name

  Ibrahim Bolaji

• Sponsor organisation

  Northern Lincolnshire & Goole Hospitals NHS Foundation Trust

• Eudract number

  2009-017459-84

• ISRCTN Number

  n/a

• Research summary

  Symphysis Pubis Dysfunction (SPD) is a common and debilitating condition affecting pregnant women. It is a painful condition and has a potential to lead to significant physical and mental morbidity, causing depression , social Isolation and has a potential impact on bonding of mother and baby after delivery. Management options include simple analgesics, physiotherapy and external support, however none of these are effective in the management of moderate to severe SPD. Stronger painkillers like ibuprofen (Non steroidal anti-inflammatory), morphine etc. are avoided in pregnancy due to their serious adverse effects on the developing fetus. Debilitating symptoms sometimes lead to woman demanding premature delivery including Caesarean Section. Corticosteroids have been used in past 4 decades for treatment of SPD especially in post partum period with good outcome. Our study is a prospective, pilot study of 10 consecutive women with moderate to severe SPD at gestation age of 28 weeks or more. If the results of this treatment prove to be effective it will inform a larger study and there is a potential that this could become future alternative therapy for treating women with moderate to severe SPD.

• REC name

  Yorkshire & The Humber - Leeds East Research Ethics Committee

• REC reference

  10/H1306/67

• Date of REC Opinion

  13 Apr 2011

• REC opinion

  Further Information Favourable Opinion