Gamma Delta T cells and the APR to IV bisphosphonate final v1.6

• Research type

  Research Study

• Full title

  An in-vitro observational pilot study of the role of gamma delta T cells in the acute phase reaction to intravenous bisphosphonate; in blood samples donated by patients receiving intravenous bisphosphonate treatment for Paget’s disease or Osteoporosis final Version 1.6

• IRAS ID

  15255

• Contact name

  Jane Turton

• Sponsor organisation

  Research and Development Office Cardiff and Vale NHS Trust

• Eudract number

  2009-017369-47

• ISRCTN Number

  1

• Research summary

  We intend to perform an observational study of our patients who attend the bone treatment unit, to have intravenous bisphosphonate treatment for either osteoporosis or Paget's disease of bone. We will be studying the activity of the Participants white blood cells in the samples of blood they donate and reviewing their quality to life. We will ask the study Participants to record any flu like symptoms they have following their treatment on a chart.

• REC name

  Wales REC 2

• REC reference

  10/WSE02/65

• Date of REC Opinion

  15 Nov 2010

• REC opinion

  Favourable Opinion