Gait, instability and outcomes in total knee replacement (v 1.0)

  • Research type

    Research Study

  • Full title

    The association of gait kinematics, instability and patient reported outcomes in patients with total knee replacement.

  • IRAS ID

    255035

  • Contact name

    David Bruce

  • Contact email

    djb203@bath.ac.uk

  • Sponsor organisation

    University of Bath

  • Clinicaltrials.gov Identifier

    NCT03896191

  • Duration of Study in the UK

    2 years, 3 months, 31 days

  • Research summary

    It is unclear why 20% of patients with total knee replacements (TKR) are dissatisfied. Some have repeat knee replacement surgery to try and make the symptoms better. However, few studies have accurately assessed the way people walk with an 'unhappy' unstable knee or following re-do TKR surgery.

    The questions are:

    Does a redo knee replacement change walking patterns and is this related to patient satisfaction?
    Is there a difference in the way patients walk if they have a stable or an unstable knee replacement?

    This exploratory project uses 3D infrared cameras to analyse differences in walking patterns between these patients and patients who are satisfied with their TKR. It will also look at changes before and after re-do TKR surgery and whether there relates to a change in patient satisfaction.

    Patients attending Southmead Hospital for knee replacements will be invited to participate. One group will be due to have a re-do knee replacement because their knee replacement is unstable. They will be assessed before and after their re-do surgery. They will be compared to another group of patients who are satisfied and have a stable knee replacement. The participants in this project will be asked to answer a questionnaire about how they feel about their knee. They will have reflective markers placed on their legs and be asked to walk on a treadmill for around three minutes, so that special cameras can accurately measure how they walk.

    Understanding how changes in walking is linked to recovery could give us a way to measure a patient’s progress and guide treatment decisions.

    The study will be funded by the researcher and the NHS has kindly agreed to use of clinical areas in Southmead hospital.

  • REC name

    North West - Preston Research Ethics Committee

  • REC reference

    19/NW/0322

  • Date of REC Opinion

    7 Jun 2019

  • REC opinion

    Further Information Favourable Opinion