Gait in Fixed Or Rotating Cementless TKA (G-FORCE TKA)
Research type
Research Study
Full title
A randomised controlled trial comparing gait in fixed (Triathlon® condylar stabilised knee, Stryker, Mahwah, NJ) or rotating (Attune® Rotating Platform, DePuy Synthes Joint Reconstruction, Warsaw, IN, USA) cementless total knee arthroplasties
IRAS ID
302534
Contact name
Richard Napier
Contact email
Sponsor organisation
Belfast HSC Trust
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
4 years, 0 months, 28 days
Research summary
The number of patients requiring knee replacements is increasing every year due to the combination of an aging population, increased patient expectancy, and rising levels of obesity. Therefore, newer implants, or design features, are introduced on a regular basis to try to improve patient outcomes. In 2013, DePuy Synthes launched the Attune Knee System to provide improved range of motion and address the unstable feeling some patients experience whilst performing everyday activities, such as going down stairs. The Attune cementless rotating platform knee was first implanted in September 2016. In 2004, the first Triathlon total knee (Stryker) was implanted. The single radius design allows for mid-flexion stability. Registry figures for both the Attune and Triathlon knees are promising with good implant longevity.
To our knowledge, only one study has directly compared the Attune and Triathlon knees. Patients who received the Attune knee had a significantly shorter length of stay and operating room time, were less likely to be discharged to a skilled nursing facility and had lower hospital costs than those who received the Triathlon implant. To date, most studies comparing the Attune knee to other implants have used the PFC Sigma as a comparator and have examined cemented implants only. The majority of studies have reported no significant differences in patient-reported, functional and X-ray outcomes.
There is only a small amount of literature available on the Attune knee as it is still a relatively new implant. Worldwide, the Triathlon is widely used and is also a well-established, successful implant used in our unit. This study will help to determine whether the Attune can improve patient outcomes in terms of gait analysis, patient reported outcome measures and X-ray outcomes when compared to the Triathlon knee.
REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
24/YH/0039
Date of REC Opinion
26 Feb 2024
REC opinion
Favourable Opinion