Gait changes following a SEP in IC patients
Research type
Research Study
Full title
Does a 12-week Supervised Exercise Programme affect gait in individuals with intermittent claudication?
IRAS ID
344465
Contact name
Alastair Jordan
Contact email
Sponsor organisation
York St John University
Clinicaltrials.gov Identifier
ETH2324-0267, Institutional ethical approval
Duration of Study in the UK
1 years, 1 months, 1 days
Research summary
Peripheral Arterial Disease is a build-up of fatty deposits, called an atherosclerotic plaques, which narrow or completely block the blood vessels supplying blood to the lower limbs. A common symptom of peripheral arterial disease is intermittent claudication (IC) - a cramp-like pain in the musculature positioned ‘downstream’ of the plaque, most commonly in the calves. IC is brought on by walking, relieved by rest. Individuals with IC tend to have poorer physical function, balance and walking ability resulting in reduced quality of life when compared with age-matched controls. Individuals with IC demonstrate differences in walking gait. Differences in walking gait are responsible, in part, for an increased risk of falling the IC population when compared with age-matched population. Supervised exercise programmes (SEP) have been recommended for individuals with IC with increased physical function, walking distance until the onset of IC pain and improved quality of life cited as benefits. SEP-induced walking distances have been reported consistently, however more detailed gait analysis techniques offer deeper insights into SEP-induced changes in gait patterns and possible reduction in falls risk. The research team has developed a novel and evidence-based 12-week walking-based SEP service with York Hospital which aligns with NICE recommendations. The SEP is predominately walking over ground and walking through claudication pain, thus prolonging walking and increasing walking distances. The primary aim of this study is to determine the efficacy of the novel SEP on walking distances and changes in walking gait during pain-free, onset of pain and maximum IC pain walking using infra-red 3D optical motion analysis before and after the SEP.
REC name
London - West London & GTAC Research Ethics Committee
REC reference
24/PR/1152
Date of REC Opinion
14 Nov 2024
REC opinion
Further Information Favourable Opinion