FLOWER
Research type
Research Study
Full title
Follow-up of the Long-term Outcomes of WomEn with cardiovascular conditions in pRegnancy
IRAS ID
342413
Contact name
Paul Leeson
Contact email
Sponsor organisation
University of Oxford / Research Governance, Ethics and Assurance
Duration of Study in the UK
20 years, 0 months, 1 days
Research summary
Some women develop cardiovascular (heart and blood vessel) conditions during pregnancy, for example: high blood pressure, pre-eclampsia, heart failure or a heart rhythm disorder. Previous research has helped us understand that this leads to an increased risk of developing cardiovascular and other health problems later in life. However, there is little evidence about the timings of when these problems will occur, or whether such problems could have been predicted, or about what makes one woman more likely than another to develop further problems.
Therefore, to start to answer the above questions, we need to follow-up women who have had cardiovascular problems during pregnancy, over a long period of time, to study how their health changes, and whether there are any factors that influence this. This study therefore aims to identify all women aged over 18, who are due to deliver or have recently delivered at the John Radcliffe Hospital, Oxford, and who have been newly diagnosed with a cardiovascular condition during their pregnancy, and to follow them up over the next 20 years to study how their health changes.
The study involves collecting health information in two ways: 1) via a single telephone call with the participant (in one years’ time) and 2) through accessing participants’ medical records. We hope that the data generated will help us to better understand the timeline of health conditions after pregnancy, and to identify factors that make future health conditions more or less likely to happen.
REC name
London - Riverside Research Ethics Committee
REC reference
24/LO/0647
Date of REC Opinion
24 Sep 2024
REC opinion
Further Information Favourable Opinion