FIBRONEER-IPF

  • Research type

    Research Study

  • Full title

    A double blind, randomized, placebo-controlled trial evaluatingthe efficacy and safety of BI 1015550 over at least 52 weeks inpatients with Idiopathic Pulmonary Fibrosis (IPF)

  • IRAS ID

    1006245

  • Contact name

    Medical Information

  • Contact email

    medinfo.bra@boehringer-ingelheim.com

  • Sponsor organisation

    Boehringer Ingelheim Ltd.

  • Eudract number

    2022-001091-34

  • Clinicaltrials.gov Identifier

    NCT05321069

  • Research summary

    This study is open to adults with a lung disease called Idiopathic Pulmonary Fibrosis (IPF). People can join the study if they are 40 years or older. If they already take nintedanib or pirfenidone for their IPF, they can continue treatment throughout the study. The purpose of this study is to find out whether a medicine called BI 1015550 helps people with IPF.

    Participants are put into 3 groups randomly, which means by chance. Participants in 2 groups take different doses of BI 1015550 as tablets twice a day. Participants in the placebo group take placebo tablets twice a day. Placebo tablets look like BI 1015550 tablets but do not contain any medicine.

    Participants are in the study for up to two and a half years. During the first year, they visit the study site 10 times. Afterwards, they visit the study site every 3 months. The doctors regularly test participants’ lung function. The results of the lung function tests are compared between the groups. The doctors also regularly check participants’ health and take note of any unwanted effects.

  • REC name

    Wales REC 5

  • REC reference

    22/WA/0303

  • Date of REC Opinion

    8 Dec 2022

  • REC opinion

    Further Information Favourable Opinion