FES in chronic constipation
Research type
Research Study
Full title
The efficacy of functional electrical stimulation of the abdominal muscles in the treatment of chronic constipation in patients with multiple sclerosis
IRAS ID
136794
Contact name
Abdel Magid Bakheit
Contact email
Research summary
Chronic constipation resistant to medical treatment is common in patients with multiple sclerosis (MS). It has been reported in 43% of patients and is often associated with increased morbidity. For example, according to one study MS patients are 3 to 4 times more likely to be admitted to hospital with faecal impaction than patients with other neurological conditions. Furthermore, chronic constipation also reduces the individual’s quality of life and social participation. In a recent survey 47% of MS patients reported that they were forced to make life style changes and 15% had to give up paid employment because of the impact of constipation on their normal daily activities. \n\nThe traditional management of severe constipation is usually only partially effective and severe cases may require surgical treatment. In recent years sacral nerve stimulation has been shown to reduce chronic constipation. However, the implantation of the stimulator is an invasive surgical procedure that is associated with potentially serious complications. Functional electrical stimulation (FES)of the abdominal muscles appears a promising alternative.\n\nWe have recently studied a patient with severe chronic constipation in whom FES of the abdominal muscles increased the frequency of bowel evacuation and improved the patient’s quality of life. The purpose of this study is to further evaluate the efficacy of FES of the abdominal muscles in the treatment of chronic functional constipation and to establish its effects on gut motility.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
13/WM/0330
Date of REC Opinion
6 Sep 2013
REC opinion
Further Information Favourable Opinion