FCI in post-operative low grade gliomas
Research type
Research Study
Full title
Non-invasive in-vivo characterisation of postoperative low grade gliomas using Field Cycling Imaging (FCI)
IRAS ID
297439
Contact name
Arnab Rana
Contact email
Sponsor organisation
NHS Grampian
Duration of Study in the UK
0 years, 9 months, 30 days
Research summary
Standard MRI scanning is a very useful medical device to provide images of the brain, but it is not accurate enough to show differences between subtypes of some brain lesions.
The aim of this study is to determine whether a new imaging technique, called Field Cycling Imaging (FCI), can discriminate different low-grade gliomas and detect differences in the signal given by these lesions.
FCI is being developed by our team at the University of Aberdeen and previous pilot studies on osteoarthritis, breast cancer, musculoskeletal cancer, liver fibrosis, thrombosis and muscle damage have demonstrated that it can provide useful information for clinical diagnostics in a variety of pathologies. Additionally, our research partner BrainTECH in Grenoble, France, has found potential biomarkers of brain cancer infiltration in an ex-vivo study using FCI-based techniques. Hence, there is a solid ground to believe that FCI will provide clinically useful information in the context of brain cancer imaging.
REC name
North of Scotland Research Ethics Committee 2
REC reference
23/NS/0093
Date of REC Opinion
21 Sep 2023
REC opinion
Favourable Opinion