Faecal gut bacteria DNA testing in IBS patients and control subjects.
Research type
Research Study
Full title
Faecal gut bacteria DNA testing in IBS patients and normal (Control) subjects with the GA-map™ Dysbiosis test
IRAS ID
157589
Contact name
Guy Sisson
Contact email
Duration of Study in the UK
1 years, 0 months, 18 days
Research summary
Irritable Bowel Syndrome (IBS) is one of the most common gastrointestinal (GI) conditions in the UK. The healthcare costs associated with IBS are substantial with a large systematic review in 2003 reporting £45.6 million total direct annual costs per year in the UK (Inadomi JM et al 2003). Currently there is no direct diagnostic test for IBS and as a result it is often considered as a 'diagnosis of exclusion' with patients undergoing a varity of different tests. In addition to the additional expense the lack of a positive diagnostic test can lead to doubt in the diagnosis for both the patient and clinician. Recent insight into the causes and mecahnisms that lead to IBS have suggested that changes in the GUT bacteria might be responsible for its development. Genetic Analysis AS have developed a faecal bacteria DNA test that has the potential to positively identify patients with IBS. I t his study we aim to compare the result of faecal DNA testing in IBS patients to normal control subjects to establish whether the test can correctly identify patients who meet standard diagnostic criteria for IBS
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
15/WM/0133
Date of REC Opinion
17 Apr 2015
REC opinion
Further Information Favourable Opinion