Faecal Calprotectin variability study

• Research type

  Research Study

• Full title

  Faecal Calprotectin day-to-day variability and within sample variability study.

• IRAS ID

  150478

• Contact name

  Christine Lemaitre

• Contact email

  C.Lemaitre@shu.ac.uk

• Sponsor organisation

  Sheffield Hallam University

• Research summary

  Faecal Calprotectin analysis is performed on patient stool samples to aid clinical decisions when referring patients for colonoscopy. High faecal Calprotectin concentrations suggest irritable bowel disease (IBD) and therefore the patient is referred for colonoscopy for differential diagnosis. Previous research has suggested that FC concentrations vary, between different stool samples shed on different days and within individual stool samples. In order to explore this test further and to help service development this study aims to investigate the day to day variability of faecal Calprotectin levels within healthy volunteers and also to determine any within stool variation in calprotectin concentrations.

• REC name

  HSC REC B

• REC reference

  14/NI/1040

• Date of REC Opinion

  17 Jul 2014

• REC opinion

  Unfavourable Opinion