Factors influencing skin wound healing v1.0

• Research type

  Research Study

• Full title

  Identification of cellular and molecular factors influencing skin wound healing v1.0

• IRAS ID

  216894

• Contact name

  Paolo Matteucci

• Contact email

  Paolo.Matteucci@hey.nhs.uk

• Sponsor organisation

  University of Hull

• Duration of Study in the UK

  4 years, 11 months, 31 days

• Research summary

  This study will investigate potential cellular and molecular mediators of human skin wound healing. It builds upon extensive in vitro and animal model studies. We will use human skin that would otherwise be discarded from consenting patients undergoing reconstructive surgery. Key areas to be investigated are: regulation of skin stem cell biology, epidermal adhesion and migration, skin microbiota and extracellular matrix remodelling. Each of these areas is supported by strong preliminary data. Studies will ultimately help to identify potential new molecular and cellular targets to aid development of treatments for pathological wounds.

• REC name

  South Central - Oxford C Research Ethics Committee

• REC reference

  17/SC/0220

• Date of REC Opinion

  10 May 2017

• REC opinion

  Further Information Favourable Opinion