Extubation Failure in patients with Acute Respiratory Failure
Research type
Research Study
Full title
Extubation Failure in patients requiring intubation and ventilation for the management of acute respiratory failure: a regional retrospective cohort study.
IRAS ID
336931
Contact name
Malcolm AB Sim
Contact email
Sponsor organisation
University of Glasgow
Duration of Study in the UK
0 years, 3 months, 1 days
Research summary
This study seeks to find out the rate of extubation failure (the proportion of patients with a breathing tube who need it reinserted within 3 days after its planned removal) in patients who have required a breathing tube and breathing support via a machine due to severe breathing difficulties. It also aims to assess what factors contribute to an increased risk of extubation failure. This is an important question as potentially up to 25% of such patients experience extubation failure (with significant impact on health and resource planning) and there may be steps that can easily be taken to reduce the level of risk.
We will focus our study by reviewing the medical records of patients who required a breathing tube to be inserted for the management of severe breathing difficulties within the intensive care unit of the Queen Elizabeth University Hospital, Glasgow, over an 8-year period from 1st April 2015 to 1st April 2023. Eligible patients will be Adults (18-80 years) who had a diagnosis of severe breathing difficulty as the reason for breathing tube insertion.
This study will be performed at three hospitals within NHS Greater Glasgow and Clyde: the Queen Elizabeth University Hospital, Glasgow Royal Infirmary and Royal Alexandra Hospital. Only retrospective data will be considered.REC name
Wales REC 4
REC reference
24/WA/0162
Date of REC Opinion
12 Jun 2024
REC opinion
Favourable Opinion