Exploring the use of ECochG testing during Cochlear Implant surgery
Research type
Research Study
Full title
Exploring the use of ECochG testing during electrode insertion in Cochlear Implant surgery
IRAS ID
246326
Contact name
Manohar Bance
Contact email
Sponsor organisation
Cambridge University Hospital NHS Foundation Trust and University of Cambridge
Duration of Study in the UK
1 years, 6 months, 29 days
Research summary
Cochlear implant candidature has changed in the past years. Today many cochlear implant recipients have some low-frequency residual hearing in the ear which is to be implanted. To help preserve hearing, the electrode array must be inserted extremely carefully. It is desirable to have real-time feedback relating to progress of the electrode insertion. One possible tool that might provide this is an electrocochleography (ECochG). A brief low-frequency acoustic tone at a fixed level is delivered to the external ear canal. This results in normal movements of the outer and the inner hair cells inside the inner ear. These movements are known to produce small electrical potentials that have been previously been sensed by a recording electrode placed on the promontory, or surface of the bone in which the cochlea is located. Averaging of these recordings in synchrony with the acoustic stimulus allows the small ECochG signal to be reinforced while any physiological or electrical noise is averaged out. With ECochG measurements different aspects of the auditory system can be tested. For our work only the cochlear microphonic, generated by the outer hair cells will be recorded and analysed. The Advanced Bionics (AB) implant system is uniquely suited to do such measurements. The aim of the study is to monitor electrode array insertion during surgery and any residual hearing function over time in using this tool as a comparison to conventional methods. Subjects will undergo the study procedure of ECochG measurements, alongside additional standard of care appointments for the research, pure tone audiometry and impedence measurement. Only a 10 minute ECochG measurement will be the additional research component to the patients clinical routine as mentioned above.
REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
18/EE/0304
Date of REC Opinion
28 Nov 2018
REC opinion
Further Information Favourable Opinion