Exploring the psychophysics of keratoconus using the MEH Acuity chart.
Research type
Research Study
Full title
Exploring the psychophysics of keratoconus using the Moorfields Acuity Chart.
IRAS ID
165751
Contact name
Padraig J. Mulholland
Contact email
Sponsor organisation
Moorfields Eye Hopsital NHS Foundation Trust
Duration of Study in the UK
0 years, 11 months, 30 days
Research summary
The measurement of visual acuity is made using black letters of varying size superimposed on a uniform white background. The objective is to determine the smallest letter, or optotype, that can be correctly identified. One limitation of current tests is the variability of measurements, this making it difficult for clinicians to determine if changes in visual acuity are related to ocular disease. This variability has been attributed to the design of current optotypes, in particular their differing legibilities. Our group has recently demonstrated that a new type of letter chart (Moorfields Acuity Chart), containing letters with a black core and a white border presented on a grey background, reduces the variability of visual acuity measurements. In this study we wish to determine if changes in vision owing to keratoconus, a disease that causes the cornea to adopt an irregular shape, may be detected more easily using the Moorfields Acuity Chart compared with conventional letter charts.
REC name
London - West London & GTAC Research Ethics Committee
REC reference
15/LO/0283
Date of REC Opinion
19 Mar 2015
REC opinion
Further Information Favourable Opinion