Experiencing Seizures
Research type
Research Study
Full title
The visible manifestations and subjective seizure experience of epileptic seizures and non-epileptic attacks (NEAs).
IRAS ID
279311
Contact name
Markus Reuber
Contact email
Sponsor organisation
Sheffield Teaching Hospitals NHS FT
Clinicaltrials.gov Identifier
20089, STH
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
In previous research a modified version of the Psychosensory-Psychomotor Phenomena Interview (PPPI) was used to ask epilepsy patients about their subjective seizure experiences and found to be an effective tool to capture subjective seizure symptoms in detail. Previous research has also highlighted the potential diagnostic relevance of whether particular symptoms are freely reported or only emerge in response to prompting from a clinician. To gain a better understanding of subjective seizure experiences in Nonepileptic Attacks (NEAs) and to compare symptom reporting by patients with NEAs and those with epilepsy, we would like first to ask patients with seizure to freely report their seizure experiences before prompting them to endorse particular symptoms using the PPPI. This will allow us to compare symptom reporting in epilepsy and NEA disorder (NEAD). In addition, we will ask all participants to complete self-report measures of anxiety, depression and previous traumatization to learn more about how other conditions or experiences influence patients’ seizure experiences and how these experiences are reported. Our dataset will not only allow us to describe the breadth of seizure experiences but also to look for clustering of particular seizure experiences with other symptoms or features or other disorders (such as anxiety, depression or posttraumatic stress disorder). We will be able to compare reported and observed seizure manifestations in NEAs and epilepsy and to measure whether patients with epilepsy mention more symptoms without prompting in freely given seizure accounts than patients with NEAs.
REC name
Yorkshire & The Humber - Sheffield Research Ethics Committee
REC reference
20/YH/0119
Date of REC Opinion
26 Oct 2020
REC opinion
Further Information Favourable Opinion