Examining T cell responses in virus infection (ExCel) Version 1 [COVID-19]
Research type
Research Study
Full title
Examining T cell responses in virus infection (ExCel)
IRAS ID
280217
Contact name
Christian Ottensmeier
Contact email
Sponsor organisation
University Hospital Southampton NHS Foundation Trust
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
In recent years, many diseases have been found to be affected by how the immune system works. There are now new treatments, which target the immune system (immunotherapy). These can be used on their own or together with existing treatments. Promising results have been seen in patients with different types of diseases, including lung diseases.\n\nSo far only a small number of people benefit from immunotherapy. This is because we still do not fully understand how immunotherapy works and how to choose the right treatment for the right person. \n\nWe would like to look at blood and tissue samples from patients who are known to have a viral infection to help us better understand how the immune system works. We will compare these to samples from patients with chronic viral infections and healthy people. \n\nThe purpose of this project is to improve our knowledge of how the immune system works in lung diseases. Our long term aim is that the results will guide us to developing better treatments for a range of diseases including viral infections and cancer. \n
REC name
South Central - Berkshire Research Ethics Committee
REC reference
20/SC/0155
Date of REC Opinion
24 Mar 2020
REC opinion
Further Information Favourable Opinion