Evaluation of STH post-COVID outcomes v1
Research type
Research Database
IRAS ID
289341
Contact name
A A Roger Thompson
Contact email
Research summary
Evaluation of post-COVID outcomes at a single NHS trust
REC name
North West - Haydock Research Ethics Committee
REC reference
21/NW/0067
Date of REC Opinion
30 Mar 2021
REC opinion
Further Information Favourable Opinion
Data collection arrangements
Sheffield Teaching Hospitals is a tertiary referral centre for infectious diseases and is the regional centre for cases of COVID-19. This research database will store clinical data, obtained in the course of normal patient care, from patients attending Sheffield Teaching Hospitals with confirmed or suspected COVID-19.
STH staff use several electronic systems to collect, store and view data obtained in the course of normal patient care. Data already held on STH clinical databases include:
• demographics, including age, sex, height, weight
• medical history including comorbidities
• standard clinical physiological measurements including, breathing test and spirometry results
• exercise test data, airway reactivity measures, sleep study data
• laboratory test results e.g. blood tests, clinical chemistry
• imaging and radiological data and reports e.g. x-rays, Magnetic Resonance Imaging, CT scans
• other assessments including patient reported outcomes and measures of quality of life
• medications and treatments data
This new electronic database creates a facility that has previously not existed, i.e. a central electronic portal collating information important to clinicians, making it easier for them to access and analyse clinical data. This is a valuable resource which in summary will facilitate:
• audit and service evaluation
• data input to national disease registries
• researchResearch programme
Retrospective and prospective analysis of the routine clinical data held on the database will enable study of population health, the natural history of disease, and the safety profile and clinical and cost-effectiveness of healthcare interventions used in daily practice. We aim to support a research program with the following objectives 1) To evaluate currently used investigations for diagnosis and assessment of COVID-19 and complications of the condition 2) To examine the outcome of various treatments in different groups of patients who have had suspected or confirmed COVID-19 3) To identify potential new uses of currently used investigations and treatments 4) To use large volumes of data collected from routinely performed tests to improve our understanding of disease and improve diagnostic and treatment strategies. The objectives listed above will be achieved by systematically collecting the results of routinely performed investigations. This will enable new research questions to be created with clearly defined end points. The fields of health and social care will include primarily respiratory medicine and infectious diseases, but there may also be research in associated fields such as cardiovascular disease, physiotherapy, physiology, imaging and radiology, and health services.
Research database title
Evaluation of post-COVID outcomes at a single NHS trust