Evaluation of a POCT monitor to measure creatinine in whole blood

• Research type

  Research Study

• Full title

  Evaluation of a Point of care testing monitor to measure creatinine in whole blood

• IRAS ID

  174265

• Contact name

  Devaki Nair

• Contact email

  devaki.nair@nhs.net

• Sponsor organisation

  Royal Free London NHS Foundation Trust

• Duration of Study in the UK

  1 years, 0 months, 0 days

• Research summary

  Chronic kidney disease (CKD) is a common condition resulting due to impairment of kidney functions. The disease is usually silent and progressive. It has a prevalence of 13-14 % in UK population (Health Survey of England 2009). Early recognition of CKD would enable the initiation of the preventive measures that slow the progression of the condition. Serum creatinine (Cr) measurement has been a part of the NHS health check. POC testing for Cr could facilitate early diagnosis of CKD via screening programmes. We propose to evaluate the POC Cr measurements by testing whole blood Cr in individuals with varying levels and comparing with their laboratory measurements. We aim to recruit:
  1. 200 patients with CKD (stages 1-5)
  2. 100 post kidney transplant patients
  3. Screening in high risk patients ( DM, hypertension)- 100 patients
  4. 100 patients with amyloidosis with varying creatinine levels.

• REC name

  West of Scotland REC 3

• REC reference

  15/WS/0090

• Date of REC Opinion

  4 Jun 2015

• REC opinion

  Further Information Favourable Opinion