ETTAA
Research type
Research Study
Full title
Effective Treatments for Thoracic Aortic Aneurysms: A prospective cohort study
IRAS ID
140264
Contact name
Stephen Large
Contact email
Sponsor organisation
Papworth Hospital NHS Foundation Trust
Research summary
The research proposed in this ethics application aims to collect data on patients referred to aortic aneurysm clinics across the UK, with a thoracic aortic aneurysm of greater than 4cm. Following a detailed consent process and adequate time to make an informed decision, patients who are willing to take part in the study will be followed up over a period of 1-5 years after their referral. No additional tests will be undertaken as part of the study, but participants will be asked to provide information on their quality of life and use of NHS and social care services throughout the course of the study and before and after any surgical intervention they might have. Participants will also be asked to give permission for their medical records to be examined in detail, in order to collected information about their health status and any treatments that they have throughout the follow up period. This will include both hospital and general practice records. We aim to analyse all the information collected in order to:\n1. Understand the growth rate of aneurysms of CTAA and identify which factors influence the growth rate.\n2. Clarify the outcomes (procedure success rates and post operative complications) of ESG and OSR for CTAA in the current era.\n3. Estimate the cost-effectiveness of BMT, ESG and OSR by measuring changes in survival and quality of life of patients compared to the cost of treatment and post operative patient care.\n4. Create a risk score that will help specialists determine which intervention (stenting or surgery) is best suited to a given patient.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
13/WM/0507
Date of REC Opinion
17 Dec 2013
REC opinion
Favourable Opinion