ERICA-ARREST
Research type
Research Study
Full title
Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in out of hospital Cardiac Arrest
IRAS ID
296654
Contact name
Paul S C Rees
Contact email
Sponsor organisation
Queen Mary University of London
Clinicaltrials.gov Identifier
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Sudden cardiac arrest is a major health problem, which kills tens of thousands of people each year in the UK. Despite advances in resuscitation medicine, only 1 in 10 people survive a cardiac arrest. Improving survival rates from OHCA is a major priority for the Resuscitation Council, the British Heart Foundation and NHS England, and was identified as a key area for improvement by the Department of Health.
This study will assess the feasibility of using a special balloon device to help with resuscitation. This will be delivered, for the first time in the UK, in the field by a helicopter medical service attending patents who have suffered a cardiac arrest. Resuscitation teams from East Anglian Air Ambulance, led by a consultant, will deliver a small balloon device into the main aorta artery, using a tube placed in the top of the leg. This balloon will then be inflated, so that resuscitation efforts are focused on providing blood flow to the heart and brain. Blood pressure and brain oxygen levels will be closely monitored throughout, using invasive and non-invasive techniques.
It will be used in addition to current resuscitation treatments. We aim to study the feasibility of delivering this treatment, as well as the feasibility of measuring the body's responses to it. We hope that it will increase blood pressure and blood flow to the heart and brain, which might improve survival from cardiac arrest. The findings will help us to design future research studies. Twenty patients will be enrolled in this study.
REC name
London - Bromley Research Ethics Committee
REC reference
23/LO/0996
Date of REC Opinion
23 Jan 2024
REC opinion
Further Information Favourable Opinion