Endometriosis and ovarian reserve

  • Research type

    Research Study

  • Full title

    To assess the ovarian reserve in the patients affected by endometriosis, benign ovarian cyst, pelvic pain or pelvic adhesions before and after surgery.

  • IRAS ID

    122587

  • Contact name

    Katie Pateman

  • Contact email

    katie.pateman@uclh.nhs.uk

  • Sponsor organisation

    University College London Hospital

  • Research summary

    The ovary is generally thought of as an egg bank from which the woman draws during her reproductive life. Ovarian reserve is a term used to give the number of eggs in this egg bank a name.
    The ovarian reserve decreases normally with age, particularly over the age of 37-40 years.
    The most commonly used tests to assess this ovarian reserve are the Anti-Mullerian Hormone (AMH) and antral follicle count (AFC. The AMH is a hormone that can be measured in the blood (a blood test).
    AFC is the number of the follicles present in the ovaries at the beginning of the menstrual period which are counted on a transvaginal ultrasound examination.
    We are trying to see if having surgery for endometriosis, or for benign ovarian cysts or for pelvic pain improves the ovarian reserve.

  • REC name

    London - Queen Square Research Ethics Committee

  • REC reference

    13/LO/0898

  • Date of REC Opinion

    1 Jul 2013

  • REC opinion

    Further Information Favourable Opinion