Endometrial Blood Flow using Doppler: Acceptability & Reproducibility
Research type
Research Study
Full title
Measuring Endometrial Blood Flow using laser Doppler: Acceptability & Reproducibility (EMBeD)
IRAS ID
250444
Contact name
Mary Martha Eyo
Contact email
Sponsor organisation
Birmingham Women's and Children's Hospital
Clinicaltrials.gov Identifier
n/a, n/a
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
The aim of our research is to test whether laser doppler is a more accurate way of measuring blood flow, of the womb lining, than ultrasound. We also aim to test whether it is acceptable to patients.
Laser doppler is a thin plastic tube that fits through the womb opening and measures the blood flow to the womb lining. It does this by shining visible light onto it and measuring how much is reflected back by the blood that is moving. A previous study showed that this is more accurate than ultrasound.
To find out if a larger and more expensive study should be carried out, to investigate whether this test can tell when the womb is in the ideal condition for pregnancy, we must investigate whether:
1) Women are happy to have their womb measured by laser doppler;
2) Doctors can use laser doppler to give reliable results;
3) We are able to do everything needed to design a bigger study.This study would ask women to have their womb lining blood flow measured during a scheduled outpatient hysteroscopy appointment that they are already having for a medical reason that has already been identified. They will then be asked to complete a questionnaire, asking about their experience having the procedure. We will calculate whether the blood flow measurements taken are reliable.
If we complete this study to answer these questions, and the answers suggest that a larger study could be done, we will have the information to design the next study, making it a lower risk and more likely to be successful.
REC name
Wales REC 4
REC reference
19/WA/0038
Date of REC Opinion
13 Feb 2019
REC opinion
Favourable Opinion