Effect of Ranolazine In Heart Failure Patients with Preserved Ejection

• Research type

  Research Study

• Full title

  ERIPE:Effect of Ranolazine In Heart Failure Patients with Preserved Ejection Fraction Code: MEIN/10/Ran-Did/001

• IRAS ID

  98551

• Contact name

  John Camm

• Sponsor organisation

  A Menarini Farmaceutica Internazionale SRL

• Eudract number

  2011-000805-27

• ISRCTN Number

  No number provided

• Clinicaltrials.gov Identifier

  No number provided

• Research summary

  The study will look at the effect of Ranolazine in patients with heart failure whose heart has a problem in relaxing in order to fill with blood but has no problem in contracting to push blood around the circulation. Patients will be tested using echocardiology that uses sound waves to produce a picture of the heart. Study participants will receive standard treatment for their condition plus either the study drug or an inactive sugar coated pill (Placebo). Approximately 120 participants in 16 hospitals throughout France, The United Kingdom, Italy and Spain will take part. Four hospitals in The United Kingdom will take part each recruiting about 30 participants.

• REC name

  London - Brighton & Sussex Research Ethics Committee

• REC reference

  12/LO/1451

• Date of REC Opinion

  23 Oct 2012

• REC opinion

  Further Information Favourable Opinion