Effect of orthoses and underfoot vibration on balance in neuropathy
Research type
Research Study
Full title
The feasibility and effect of ankle foot orthoses and underfoot vibration on the postural stability of people with inherited neuropathy
IRAS ID
200182
Contact name
Gita Ramdharry
Contact email
Sponsor organisation
Joint Research & Enterprise Office St George's, University of London & St George's University Hosp.
Duration of Study in the UK
0 years, 3 months, 28 days
Research summary
Balance impairments and falls are more common in people who have Charcot Marie Tooth disease (CMT) than in people without the condition. CMT is a condition which affects the nerves causing a variety of symptoms including sensation impairments and weakness. The impairments are usually most evident in the feet and hands, but they can progress very slowly moving closer to the trunk. Ankle Foot Orthoses (AFO’s) are often prescribed to help with walking and daily function. So far the effects of AFO’s on standing balance in people who have CMT have not been looked at. Insoles are also often prescribed to realign foot deformity and reduce pain. Insoles which give a vibratory input have had a positive impact on walking in older people but have not been looked at in balance and in CMT. Insoles which give a vibration feedback to the sole of the foot when worn have been designed. This study will look at whether the use of AFO’s and the vibratory insoles have an effect on standing balance in people with CMT or related peripheral neuropathy. Balance measurements will be taken in a single session comparing a variety of postures. Patients will be recruited from neurology outpatient clinics at the National Hospital of Neurology and Neurosurgery.
REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
16/EE/0313
Date of REC Opinion
4 Nov 2016
REC opinion
Further Information Favourable Opinion