Effect of Heart Failure on Infarct Volume in Acute Stroke
Research type
Research Study
Full title
Effect of Heart Failure on Infarct Volume in Acute Stroke. A Pilot Study
IRAS ID
129305
Contact name
Patrick Pullicino
Contact email
Sponsor organisation
East Kent Hospitals University NHS Foundation Trust
Research summary
This research will investigate if people with poor heart pumping action have larger areas of brain injury after a stroke than persons with normal heart function. Heart failure (poor heart pumping action) affects nearly a million persons in the UK. There are 150,000 new strokes in the UK per year and up to 20% of these patients have heart failure. Severe heart failure is linked to poor recovery after a stroke but the cause of this is unknown. We will compare the size of brain injury after a stroke between patients with heart failure and those without on computed tomographic (CT) or magnetic resonance (MR) scans performed after the stroke. Presence of heart failure will be diagnosed by a blood test called brain natriuretic peptide (BNP) which is increased in heart failure or by clinical examination within 72 hours of stroke onset. We will determine the severity of the disability left after the stroke 12 weeks after the stroke. We will analyse the data to find the causes of severe disability or large areas of brain injury after stroke.
REC name
South Central - Oxford C Research Ethics Committee
REC reference
13/SC/0271
Date of REC Opinion
18 Jul 2013
REC opinion
Further Information Favourable Opinion