ECASS-4: ExTEND

• Research type

  Research Study

• Full title

  European Cooperative Acute Stroke Study-4: Extending the time for Thrombolysis in Emergency Neurological Deficits

• IRAS ID

  129766

• Contact name

  Christine Roffe

• Contact email

  christine.roffe@uhnm.nhs.uk

• Sponsor organisation

  Ruprecht-Karls-University Heidelbert, Medical Faculty

• Eudract number

  2012-003609-80

• Research summary

  The aim of this study is to assess the safety and effectiveness of a drug called Alteplase in patients who have suffered an ischaemic stroke. At the moment the approved window following a stroke for Alteplase to be administered is three hours. This is a short period and so this study is looking at extending that time and establish efficacy at 4.5 to 9 hours following onset, or following the patient waking up with with symptoms of a stroke (wake up stroke).

• REC name

  North West - Greater Manchester South Research Ethics Committee

• REC reference

  13/NW/0714

• Date of REC Opinion

  23 Jan 2014

• REC opinion

  Further Information Favourable Opinion