(duplicate) SUNRRISE

  • Research type

    Research Study

  • Full title

    Single Use Negative pRessure dressing for Reduction In Surgical site infection following Emergency laparotomy

  • IRAS ID

    252175

  • Contact name

    Richard J W Wilkin

  • Contact email

    r.wilkin@bham.ac.uk

  • Sponsor organisation

    University of Birmingham

  • ISRCTN Number

    ISRCTN17599457

  • Duration of Study in the UK

    2 years, 3 months, 4 days

  • Research summary

    Aim
    This study aims to test whether the use of a new type of active wound dressing (Single Use Negative Pressure Dressings ‘SUNPDs’) can reduce rates of wound infection (also called surgical site infection or ‘SSI’) after emergency surgery on the abdomen (tummy).

    Background
    Emergency abdominal operations are performed for a variety of life threatening indications, including bowel blockages or perforations, traumatic injuries and major infections. Patients are left with large wounds on the abdomen and at least 1 in 4 of which will become infected. These SSIs are painful and take longer to heal, often resulting in a longer hospital stay and greater need for further wound care in the community. In an already unwell patient, development of an SSI can contribute to other major medical complications or even death.
    The SUNPDs are a special type of closed wound dressing that have recently been developed. They provide gentle suction to the closed wound and may help prevent development of an SSI. Negative pressure dressings are already used for some types of wounds and have been proven to be safe. However, they are more expensive so we need to be sure that that they are effective in reducing SSI in abdominal wounds before widespread uptake can be recommended within the NHS.

    Methods
    We are proposing a study to compare these new dressings against standard dressings in patients undergoing emergency abdominal operations to establish whether they are effective in reducing SSI rates. We will compare the number of SSIs and the overall costs of treatment between the two groups and the acceptability of the dressings to both patients and health professionals.

    Our findings will be published in international medical journals so that they can help patients globally.

  • REC name

    Scotland A: Adults with Incapacity only

  • REC reference

    19/SS/0065

  • Date of REC Opinion

    28 Jun 2019

  • REC opinion

    Favourable Opinion