(duplicate) Roles of Growth factor Receptors in the Progression of Ova
Research type
Research Study
Full title
Investigation of the roles of cancer stem cells and EGFR family members in the progression of ovarian cancer and response to therapeutic interventions
IRAS ID
141050
Contact name
Sharadah Essapen
Contact email
Sponsor organisation
University of Kingston, London
Research summary
Ovarian cancer is the fifth most common cancer in women, with approximately 6,500 new cases in the UK each year.In 2008, ovarian cancer was responsible for 4,400 deaths in the UK, and so it is poses a serious health risk. In spite of initial good responses to conventional chemotherapy, the majority of patients will develop resistance to the chemotherapy, and ultimately die of their disease.
Therefore, to reduce ovarian cancer mortality, it is imperative to conduct more in depth studies, and to have a better understanding of the underlying molecular mechanisms and various cell signalling pathways which are altered in this disease. This PhD research project aims to investigate and identify biological marker(s) which are important in the progression of ovarian cancer, and those that might be helpful in its early detection. This information may allow us to develop novel and more specific therapeutic strategies (i.e. targeted therapy) for this disease.REC name
North West - Preston Research Ethics Committee
REC reference
13/NW/0873
Date of REC Opinion
6 Jan 2014
REC opinion
Favourable Opinion