Kinematics of silastic joint replacements in the hand

• Research type

  Research Study

• Full title

  Defining in vivo kinematics of single piece silastic finger joint replacement with magnetic resonance imaging

• IRAS ID

  258711

• Contact name

  Ian Trail

• Contact email

  Ian.Trail@wwl.nhs.uk

• Sponsor organisation

  Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust

• Duration of Study in the UK

  0 years, 5 months, 31 days

• Research summary

  Joint replacement surgery in the finger is carried out for pain relief in severe arthritis; this can either be degenerative or rheumatoid arthritis.
  There are several options for joint replacement currently licensed for use in the UK, but national data is not collected so the exact numbers and failure rates are unknown. Data from the Norwegian joint registry indicates that 99% of finger joint replacements are single piece silastic (silicone) implants. Research suggests these implants break or fracture at, or around, the hinge. This is true of explants (broken implants removed from patients) and in vitro (laboratory based) simulator testing.
  This research intends to define
  •
  • The displacement of single piece silastic joint replacements in vivo with static Magnetic resonance imaging (MRI) scan
  • Compare the kinematics of silastic joint replacements with native joints

  Patients will be recruited from those patients who remain in clinical care at the research site. They will be asked to attend the research site. During that visit the participant will be asked to answer a questionnaire about their hand function, undergo an examination of their hand movement and have an MRI scan of both hands. We anticipate recruiting ten patients who have had a single piece silastic replacement with an normal joint on the other hand for comparison.
  Due to the uncommon nature of the operation we will allow six months for the recruitment of patients.
  The visit for the research study will require one additional appointment with reimbursement for travel costs and this will not affect any scheduled appointments with their operating surgeon. All information required for the study will be collected at the research visit and we do not anticipate the need for any further contact from the research team following this.

• REC name

  North East - Newcastle & North Tyneside 1 Research Ethics Committee

• REC reference

  19/NE/0340

• Date of REC Opinion

  22 Nov 2019

• REC opinion

  Favourable Opinion