Drug susceptibility of imported malaria parasites from UK travellers
Research type
Research Study
Full title
Drug susceptibility and genetic diversity of imported malaria parasites from UK travellers
IRAS ID
246500
Contact name
Colin J Sutherland
Contact email
Sponsor organisation
London School of Hygiene & Tropical Medicine
Duration of Study in the UK
1 years, 10 months, 18 days
Research summary
The study seeks to grow malaria parasites (Plasmodium species) from UK malaria patients in the laboratory to enable studies of drug susceptibility. We will use these parasites, growing in our culture dishes, to test current and new antimalarial drugs against clinically relevant parasites from patients we see today rather than testing against older parasites which were mainly collected in the 1970s and 1980s. Established growth cultures will also allow us to generate genome sequence information for these "modern" parasites, and this is particularly useful for the lesser studied species of malaria parasite.
REC name
London - Chelsea Research Ethics Committee
REC reference
18/LO/0738
Date of REC Opinion
30 Apr 2018
REC opinion
Favourable Opinion