Does hand grip strength change over a haemodialysis session?
Research type
Research Study
Full title
Does hand grip strength change over the course of a haemodialysis session?
IRAS ID
198747
Contact name
shashivadan Hirani
Contact email
Sponsor organisation
City University London
Duration of Study in the UK
0 years, 8 months, 27 days
Research summary
Title
Does handgrip strength change over haemodialysis?
Background
Prevalence of malnutrition in patients undergoing haemodialysis (HD) occurs in more than 50% of the population, with higher risks of morbidity and mortality. Current measures used to assess malnutrition in this patient group have limitations, resulting in the potential for under-diagnosis, delaying nutritional support, and compromising outcome. The use of Hand grip strength (HGS) is a non-invasive, bed-side test, and is associated with nutritional status and survival. Before it is possible to investigate its ability to measure malnutrition, however, the change in grip strength measured at different times during HD must first be established, and forms the basis of the research proposal.Methodology
A within subjects, repeated measures observational study, measuring HGS over the course of a HD session, on 2 separate HD sessions, one month apart.An additional component of the study is a comparison of HGS over time in a control group, to measure the natural change in HGS over time.
- HD participants
All participants will have their HGS measures taken on a mid-week dialysis day, on the non-fistula arm, or dominant arm in those without a fistula.Participants will have their HGS test taken just before dialysis, just after completing dialysis and 5 times during dialysis. Each set of measures will be taken 3 times and the highest score recorded.
Data will also be collected from the medical records. This includes date of birth, gender, cause of renal disease, dialysis vintage, routine dialysis blood results, weights and blood pressure measurements.
- Control participants
Participants in this group will have their HGS measures taken over a 4 hour time period as described above. They will be asked to be seated with minimal activity to make it comparable to the HD group.They will also have gender, age, ethnicity, weight and height recorded as reported by the participant.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
16/YH/0071
Date of REC Opinion
15 Feb 2016
REC opinion
Favourable Opinion