Does extra fine HFA-BDP suppress small airways inflammation in COPD?

• Research type

  Research Study

• Full title

  Does extra fine HFA-BDP suppress small airways inflammation in COPD?

• Eudract number

  2008-005909-19

• Research summary

  In COPD, significant inflammation is present in the small airways. Recent advancement in measuring techniques means that a surrogate value of this inflammation can now be obtained, non-invasively.Many inhalers delivery medicines that are relatively large particles. Large particles are deposited in larger airways, and may not therefore reach the areas of the lung we would wish to target. We wish to target these small airways using anti-inflammatory (steroid) inhalers that delivery the medicine as very fine particles.We will compare these effects to a short course of systemic steroid tablets as well as a placebo.

• REC name

  East of Scotland Research Ethics Service REC 1

• REC reference

  08/S1401/139

• Date of REC Opinion

  30 Dec 2008

• REC opinion

  Favourable Opinion