Does Dietary intervention reduce Nausea and Vomiting in Pregnancy?
Research type
Research Study
Full title
Pilot study of Dietary intervention for the control of Nausea and Vomiting in early Pregnancy
IRAS ID
163339
Contact name
Una Poultney
Contact email
Sponsor organisation
North Cumbria University Hospitals NHS Trust
Clinicaltrials.gov Identifier
, 15/NW/0273
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Nausea and vomiting in early pregnancy (NVP) affects about 80% of all women who are pregnant (Temming et al., 2014). The reasons pregnant women experience nausea and vomiting are not well understood. Many women report that the symptoms of nausea and vomiting in pregnancy can have a major impact on their lives (Lacasse et al., 2008; Matthews et al., 2014). Pregnant women are often advised to make dietary changes during pregnancy, but there is no current evidence that dietary changes can help reduce nausea and vomiting during pregnancy (NICE, 2013).
Safe effective approaches for the treatment of nausea and vomiting in pregnancy are required. This pilot study aims to assess the effect of dietary intervention on nausea and vomiting in early pregnancy (Matthews et al., 2014; Maltepe and Koren, 2013; NICE, 2013; King and Murphy, 2009).
Ten free living pregnant women over 18 years of age who have uncomplicated normal pregnancies will be recruited from the local NHS antenatal clinic. Potential participants will be approached consecutively over a planned 3 month period, and provided with a patient information sheet. Interested patients will then meet with the researcher in the antenatal clinic who will further explain the study.
Participants will be asked about their eating habits, their nausea and vomiting symptoms in pregnancy (NVP) and how NVP affects their quality of life. Women will then be asked to try a list of standardised dietary recommendations and a sample meal plan based on current UK guidelines for two weeks. Following the dietary intervention, women will be reviewed to reassess their current eating habits, nausea and vomiting symptoms in pregnancy (NVP) and how the NVP affects their quality of life.
The information gained from this pilot study will contribute to the evidence base for effective dietary interventions in early pregnancy (Matthews et al., 2014; NICE, 2014).
References
King, T.L and Murphy, P.A. (2009) ‘Evidence-based approaches to managing nausea and vomiting in early pregnancy’. Journal of Midwifery and Women's Health. 54(6), pp430-44. doi:10.1016/j.jmwh.2009.08.005Lacasse A., Rey, E., Ferreira, E., Morin, C and Bérard, A. (2008) ‘Validity of a modified Pregnancy-Unique Quantification of Emesis and Nausea (PUQE)
scoring index to assess severity of nausea and vomiting of pregnancy’. American Journal of Obstetrics and Gynaecololgy.198,71.e1-71.e7. doi:10.1016/j.ajog.2007.05.051Maltepe, C and Koren, G. (2013) ‘Preemptive treatment of nausea and vomiting of pregnancy: results of a randomized controlled trial’. Obstetrics and Gynaecology International. 2013. p1-8.doi:10.1155/2013/809787
Matthews, A., Haas, DM., O'Mathúna, DP., Dowswell, T and Doyle, M.(2014) ‘Interventions for nausea and vomiting in early pregnancy’. Cochrane Database of Systematic Reviews 2014, Issue 3. Art. No.: CD007575. doi: 10.1002/14651858.CD007575.pub3
National Institute for Health and Care Excellence (NICE) (2013) ‘Nausea/ vomiting in pregnancy’. National Institute for Health and Care Excellence. Available at http://cks.nice.org.uk/nauseavomiting-in-pregnancy#!topicsummary. (Accessed 6th June 2014)
Temming, L., Franco, A., Istwan, N., Rhea, D., Desch, C., Stanziano, G and Joy, S. (2014) ‘Adverse pregnancy outcomes in women with nausea and vomiting of pregnancy’. Journal Of Maternal-fetal & Neonatal Medicine. 27(1), pp84-8.doi: 10.3109/14767058.2013.806473
REC name
North West - Preston Research Ethics Committee
REC reference
15/NW/0273
Date of REC Opinion
5 May 2015
REC opinion
Further Information Favourable Opinion