Documentation of hepatic encephalopathy in clinical practice

  • Research type

    Research Study

  • Full title

    An observational study to assess documentation of hepatic encephalopathy in clinical practice

  • IRAS ID

    165904

  • Contact name

    Bruce Scharschmidt

  • Contact email

    Bruce.Scharschmidt@hyperiontx.com

  • Sponsor organisation

    Hyperion Therapeutics

  • Duration of Study in the UK

    1 years, 5 months, 1 days

  • Research summary

    This is a non-interventional, multi-center study, to be conducted in up to 20 countries and up to 130 sites, to collect data on how clinicians document signs and symptoms of overt HE in clinical practice.
    It is designed to permit all qualified and interested clinician providers to participate as investigators, and all interested patients to participate.
    Patients will be followed per usual medical practice and evaluated for overt HE episodes in the course of their care. There will be no study specific visits, labs or tests administered as a requirement of participation.
    Patients enrolled in this study will be required to provide access to their health information, including prospective data collection, for up to 12 months and the review of their medical history for 30 days prior to consent.
    The study will last up to 12 months for each patient, i.e. consenting
    patients who experienced an episode of overt HE within the last 30 days will be enrolled and their HE episodes recorded for up to 12 months.

  • REC name

    London - Surrey Borders Research Ethics Committee

  • REC reference

    14/LO/2159

  • Date of REC Opinion

    12 Dec 2014

  • REC opinion

    Favourable Opinion