Digital therapeutic tools for the treatment of depression and anxiety

  • Research type

    Research Study

  • Full title

    Digitising paper-based tools in common use for the treatment of mild to moderate depression and anxiety disorders: an investigation of efficacy and acceptability

  • IRAS ID

    275982

  • Contact name

    Valentin Tablan

  • Contact email

    v.tablan@iesohealth.com

  • Sponsor organisation

    Ieso Digital Health Ltd

  • ISRCTN Number

    ISRCTN87336732

  • Duration of Study in the UK

    1 years, 6 months, 0 days

  • Research summary

    Mental health disorders constitute an enormous healthcare concern, with one in four people estimated to be affected. Despite their high prevalence, government spending on mental health remains low and access to care remains poor globally. Even in the UK, only 1 in 5 adults with a mental health disorder have access to psychological therapy like cognitive behavioural therapy (CBT). However, delivery of therapy by computers and mobile phones is helping to improve access.

    The current study, aims to explore the use of computer/mobile-based therapy tools to enhance the effectiveness of CBT for the treatment of common mental health disorders such as depression and anxiety.

    The aims of the study are as follows:

    1) Convert existing paper-based therapeutic tools commonly used for the treatment of depression and anxiety disorders, such that they can be delivered by a computer as support tools to CBT delivered by a qualified clinician;

    2) Evaluate the effectiveness of CBT enhanced by such digital therapeutic tools in reducing symptoms of depression and anxiety disorders in a safe environment, under the supervision of a qualified clinician;

    3) Assess the acceptability of digital therapeutic tools and the degree to which patients are willing to engage with these during therapy.


    This study will recruit patients with mild-to-moderate depression or anxiety disorders to receive CBT, delivered by a therapist over the internet. The course will generally consist of 8 to 10 one hour sessions. Patients will receive either:

    a) A course of CBT, delivered by a qualified clinician and enhanced by one of six possible digital therapeutic tools, consisting of digitised versions of paper tools already commonly used by therapists in the treatment of the disorder.

    b) A course of CBT, delivered by a qualified clinician, without the additional digital tools.

  • REC name

    West of Scotland REC 5

  • REC reference

    20/WS/0076

  • Date of REC Opinion

    18 Jun 2020

  • REC opinion

    Further Information Favourable Opinion